Outlook 2016 opens with “Something is wrong with one of your data files and outlook needs to close.

The solution was as follows:

  1. In regedit, go to: Computer\HKEY_CURRENT_USER\SOFTWARE\Microsoft\Office\16.0\Outlook\PST
  2. Delete the following two keys: LastCorruptStore and PromptRepair
  3. Start Outlook

That’s it.

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